Differential Gene Expression in GPR40-Overexpressing Pancreatic β-cells Treated with Linoleic Acid

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Differential Gene Expression in GPR40-Overexpressing Pancreatic β-cells Treated with Linoleic Acid

"G protein-coupled receptor 40" (GPR40), a receptor for long-chain fatty acids, mediates the stimulation of glucose-induced insulin secretion. We examined the profiles of differential gene expression in GPR40-activated cells treated with linoleic acid, and finally predicted the integral pathways of the cellular mechanism of GPR40-mediated insulinotropic effects. After constructing a GPR40-overe...

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ژورنال

عنوان ژورنال: The Korean Journal of Physiology & Pharmacology

سال: 2015

ISSN: 1226-4512,2093-3827

DOI: 10.4196/kjpp.2015.19.2.141